OFF-LABEL PRESCRIBING OF SSRIs TO CHILDREN: SHOULD PEDIATRIC TESTING BE REQUIRED, OR ARE THERE OTHER MEANS TO A SAFER END FOR CHILDREN?
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چکیده
(―SSRIs‖). 3 The study consisted of a thorough review of published and unpublished controlled clinical trials of antidepressants, and involved nearly 4,400 children and adolescents. 4 The results of the study suggested that suicidal behavior and ideation was twice as likely in children with Major Depressive Disorder (―MDD‖) who were prescribed off-label SSRIs. 5 Though the results were statistically insignificant, and thus could have occurred by chance alone, the increase—from 2% in children who received placebos, to 4% in children taking SSRIs—was a 100% increase, proportionally. 6
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تاریخ انتشار 2011